Ανακοινώσεις

Buy drug ativan 2mg online with prescription - with Prices & Reviews


Buy drug ativan 2mg online with prescription
96% like it View all 1709 reviews $0.26 - $3.87 per pill

want to buy ativan in florida


Major classes of antihypertensive medicinalproductswere studied, including buy cheap ativan online with american express calcium channel blockers (amlodipine), angiotensin convertingenzyme (ace) inhibitors (enalapril), beta-adrenergic receptor blockers (metoprolol), thiazidediuretics (bendrofluazide), and angiotensin ii receptor blockers (various types and doses, alone or incombination with thiazides, calcium channel blockers, beta-blockers, and/or alpha-blockers). (7 grs.tartaric acid is prescribed with the carbonates and bicarbonates to formeffervescent draughts; the tartaric acid ought to be slightly in excess in orderto lend its pleasant acid taste, the usual proportion being about eight partsof acid to seven parts of sodium bicarbonate. Free Courier shipping for all buy drug ativan 2mg online with prescription orders over $300. There is no good drug available nor in development at thismoment) or it can be small (e. Subjects who hadsuccessfully completed the previous doxazosin interaction study (using tablet 50 mg),including no significant hemodynamic adverse events, were allowed to skip dose period 1.treatment with doxazosin continued for at least7 days after dose period 1. Should be used.0050. Ammonium chloride is generally credited with actingon the secretions of the stomach and of the bronchial mucous mem-brane, which it is said to render more fluid and less tenacious, and atthe same time buy drug ativan 2mg online with prescription to increase considerably. The general result is that the total amount of blood circulatingtracings of the blood-pressure and the volume of the leg and of the spleen of the dogunder strophanthus. Protoveratrine seems tocause less irritation of the sensory terminations than veratrine, and thesubsequent local anaesthesia is more complete.the nausea and vomiting, which are invariably present in veratrinepoisoning, may be due in part to the irritation of the sensory termi-nations of the stomach, but must probably be attributed for the chiefpart to central action. For example, buy drug ativan 2mg online with prescription certain medicinal agents that have an objectionable taste have been madetable 21-4. Theprimary buy drug ativan 2mg online with prescription increase in respiration is a reflex phenomenon, dependent upon the local irritant action of the drug. (yiiz)' average (u.fluideztractum buchu (u.uva ursi (u.), leaves of arctostaphylos uva ursi or bearberry.fluidextractum uva ursi (u. The purpose of the lorazepam 1mg online legally phase iii stage is to secure data froma larger number of patients on efficacy and incidence of side effects. As theability of particles to come together and form a floc depends ontheir surface charge, zeta potential measurements on the suspension, as an electrolyte is added, provide valuable information as to the buy drug ativan 2mg online with prescription extent of flocculation in the system.this principle is illustrated by reference to the following example, taken from the work of haines and martin.2 particles ofsulfamerazine in water bear a negative charge. The difference in rhythm of the two divisionsleads buy drug ativan 2mg online with prescription to a very characteristic periodic variation in the strength of thecontractions of both auricle and ventricle (fig. Lead lorazepam maximum dose optimisation is the last phase in drug discovery before the buy drug ativan 2mg online with prescription drugmolecule is transferred to early development. Nih is one of the world's foremost medical research centers. — the general action of bismuth has been studied in animals by tt subcutaneous or intravenous injection of the double salts, such as the tartr;of bismuth and sodium. It buy drug ativan 2mg online with prescription antagonizes the dilatation of the pupilafter homatropine and cocaine much more successfully than that dueto atropine. Theincrease in electrostatic repulsion between nonpolar particlesdue to the adsorption of surface-active ions stabilizes the dispersion against coagulation. No clinically significant adverse effects were observed and no dose adjustment is buy drug ativan 2mg online with prescription required.rifabutin: tremendous buy drug ativan 2mg online with prescription increase in the flow of urine in dropsicalconditions due to uncompensated heart. Paul didn't want to accept the reality of his impotence, and soma seizure neither did ellen. However, other factors such assurgical stimulation, intravascular volume status, blood oxygenlevels, and withdrawal of perioperative (3 blockers, may tilt theoxygen supply-demand balance toward myocardial ischemia.halothane and, to a lesser extent, other volatile anestheticssensitize the myocardium to epinephrine and circulatingcatecholamines. Individed doses of £-f grs. The active principlesstand buy drug ativan 2mg online with prescription in no less need of being assayed. It differs from most poisons inacting for the most part on certain phases of the buy generic ativan 1mg online in usa animal metabolism,and it is believed that the liver buy drug ativan 2mg online with prescription is the chief seat of its activity.phosphorus is absorbed with difficulty, because it is buy drug ativan 2mg online with prescription very insolublein water and the body fluids and is only slowly volatilized at ordinarybody temperature. Stability of a pharmaceutical product may be defined as thecapability of a particular formulation, in a specific container/closure system, to remain within its physical, chemical, mi-crobiological, therapeutic, and toxicological specifications ata defined storage condition. 83of a leg or of laparotomy. Finally,with further ganglionic paralysis, the heart becomes irregularand weaker imtii it stops entirely.the temperature is lowered by aconitine, probably due to thebeginning of collapse.fibrillary twitchings of the skeletal muscles are usually presentin both buy drug ativan 2mg online with prescription cold and warmblooded animals and are due to a stimulation of the motor nerve endings. The breaking up of flocs or buy drug ativan 2mg online with prescription secondary particles isdefined as deflocculation or peptization. Steep dose-response curves inpatients can result from cooperative interactions of several differ-ent actions of a drug buy drug ativan 2mg online with prescription (eg, effects on buy drug ativan 2mg online with prescription brain, heart, and peripheralvessels, all contributing to lowering of blood pressure). Investigational drugs should be manufactured, handled and stored in accordance withgmp and used as prescribed in the study protocol.independent ethics committee /institutional review board ( iec/irb )an independent ethics committee /institutional review board (iec/irb)is a committee of experts that reviews whether the proposed study is scientifically sound. In this case, the blood levels of the uncoatedtablet were depressed markedly, while the film-coated and en-teric-coated tablets showed relatively little difference in bloodlevels.from this second study, it might be concluded that film coat-ing appears to impart the same degree of acid stability as anenteric coating. This categoryimplies possible clinical applicability in body sites where the drug is physiologically concentrated or insituations where high dosage of drug can be used. Differential effects of a misattribution manipulation on sexually functional and buy drug ativan 2mg online with prescription dysfunctional men. This sulpho-haemoglobin possessesa characteristic spectrum, marked by a dark line in the red to the left of thed line. This patient had been taking minoxidil, a potentvasodilator, during the study. This symptom is not marked in frogs, but may be so developedin mammals as to simulate convulsions, and is due to stimulation of thesame receptors as are affected by curara, as is shown by the fact thatthe buy drug ativan 2mg online with prescription twitching is arrested by this drug. Persons exposed to a very dilute vapor ofsulphuretted hydrogen suffer from local irritation of the eyes, nose and throat,indicated by pain and congestion of the conjunctiva, sneezing, purchase ativan oklahoma city dryness andsoreness of the mouth and throat, and a reflex increase in the secretion of tears,saliva, and mucus. Theseregulations, still in effect today, present the minimum require-ments to be met buy drug ativan 2mg online with prescription by industry when manufacturing, packaging,and holding human and veterinary drugs. This rise in blood-pressure is for the most part due to constrictionof the vessels of tee abdominal cavity, but an increase in the efficiencyof the heart often plays a part, though a subordinate one. He also had high blood pressure for which he was on beta blockers. The anaesthesiawith ether or chloroform is usually preceded, if not by morphineand scopolamine, by the use of some much more rapidly actingvolatile anaesthetic, as nitrous oxide, ethyl chloride, etc. At low levels, they are signalling molecules, and at high levels, they damage organelles, particularly the mitochondria. — coniine does not possess any action of importance on buy ativan washington the centralnervous system. Thank you, ARISE, for being a place where the joy of the Lord is truly infectious and inspires people, young and old to worship God together. Up to 8. Journ., hi, p. It where to buy tramadol 200mg online legit is also possible that the low dht levels where to purchase ativan 2mg in london observed in postmenopausal women are responsible for the lack of significant response to finasteride. Order ativan 2mg online legit it is excreted in theurine, the bile, the secretion of the intestinal epithelium, in the milkand saliva, and buy drug ativan 2mg online with prescription in traces in the perspiration.chronic lead poisoning is the commonest of all forms of metallifpoisoning, and at the same time one of the most insidious. Ip 3 is inactivated by dephosphory-lation; diacylglycerol is either phosphorylated to yield phosphatidicacid, which is then converted back into phospholipids, or it isdeacylated to yield arachidonic acid; ca 2+ is actively removed fromthe cytoplasm by ca pumps.these and other nonreceptor elements of the calcium-phos-phoinositide signaling pathway are of considerable importance inpharmacotherapy. Inmen treated with propecia, the maximum improvement in hair count compared to baseline wasachieved during the first 2 years.although the buy drug ativan 2mg online with prescription initial improvement wasfollowed by a slow decline, haircount was maintained above baseline throughout the 5years of the studies. The results show that the film coat-ing does not impart the degree of acid stability that the entericcoating does when the tablets are administered where to purchase ativan 2mg with mastercard immediately af-ter food in a typical clinical situation. They resemblethose seen under the antipyretics, but seem to be less frequently elic-ited buy drug ativan 2mg online with prescription by salicylic acid.

order ativan in the uk


Heart failure is an end result of many diseases (not only of themyocardium, pericardium and valves, but also of extracardiacdisorders, including systemic want to buy ativan 2mg with paypal or pulmonary hypertension,fluid overload, vascular shunts, anaemia and thyrotoxicosis).the most common of these are ischaemic heart disease(chapter 29), idiopathic congestive cardiomyopathy andcor pulmonale (chapter 33). The depression and muscular weaknesswhich is seen in animals under large doses probably arise from affectionof lower parts of the central nervous system and resemble the conditionknown as collapse more than that of narcosis.the muscular twitching seems to be entirely independent of thecentral nervous system, for it is buy drug ativan 2mg online with prescription not prevented by division of the motornerves. Primary stimulaiion of the centres in themedulla quickly followed by intense depression, producing death byfailure of respiration.— physostigmine has beenused in the past in various diseases of the nervous s3rstem, buy ativan 1mg in singapore butwithout much success. The othermechanism mediates responses to nitric oxide (no; see chapter19), where to buy ativan 2mg with visa which is generated in vascular endothelial cells in response tonatural vasodilator agents such as acetylcholine and histamine.after entering the target cell, nitric oxide binds to and activates acytoplasmic guanylyl cyclase.asodilating drugs, such as nitroglycerin and sodium nitroprus-side used in treating cardiac ischemia and acute hypertension, actby generating or mimicking nitric oxide. In cases ofpoisoning the heart is stated to be very slow and irregular, and this caneasily be elicited in anaesthetized animals by the injection of aconitineintravenously. 8llimbs, and even inability to buy drug ativan 2mg online with prescription stand, accompanied by tremors,general muscular twitchings, and at last convulsions, imconsdousness and death from stoppage of respiration. When molecular oxygen is involved, the reaction43stability of pharmaceutical productsis buy drug ativan 2mg online with prescription known as auto-oxidation because it occurs spontaneously,though slowly, at room temperature.oxidation, or the loss of buy drug ativan 2mg online with prescription electrons from an atom, frequentlyinvolves free radicals and subsequent chain reactions. However, since some older individuals experience reduced renal buy drug ativan 2mg online with prescription function by virtue of their advanced age, care should be taken in dose selection for elderly patients, and renal function monitoring may be useful in these patients [see dosage and administration and clinical pharmacology]. Protein binding is independent of total drug concentrations.based upon measurements of sildenafil in buy drug ativan 2mg online with prescription semen of healthy volunteers 90 minutes after dosing,less than 0.001% of the administered dose may appear in the semen of patients.metabolism and excretion:sildenafil is cleared predominantly by the cyp3a4 (major route)and cyp2c9 (minor route) hepatic microsomal isoenzymes. Following administration of a single dose of cipro xr, ciprofloxacin concentrations in urine collected up to 4 hours after dosing averaged over 300 buy drug ativan 2mg online with prescription mg/l for both the 500 mg and 1000 mg tablets; in urine excreted from 12 to 24 hours after dosing, ativan muscle relaxant dosage ciprofloxacin concentration averaged 27 mg/l for the 500 mg buy drug ativan 2mg online with prescription tablet, and 58 mg/l for the 1000 mg tablet.four metabolites of ciprofloxacin were identified in human urine. The patientcomplains of general weakness and faintness; the pulse is weak, theliver extends far below the ribs, and the urine shows characteristicchanges.the nose, bowel,uterus and under the skin, and eventually a condition of collapse buy cheap lorazepam 1mg online legally andfatal coma follows. The quickening of thepulse is buy drug ativan 2mg online with prescription probably caused by a stimulant action on the acceleratornerves. A change in buy drug ativan 2mg online with prescription particle morphol-ogy, aggregation and sedimentation impacts the dissolution of the activeingredient and buy drug ativan 2mg online with prescription consequently its bioavailability.nanosuspensions may improve the dissolution and as a consequence thesystemic availability of the active ingredient. The commercial focus of health care, also adopted the pre buying habit of comparing goods and services, on the internet. They can be dangerous if you have certain health problems or you're taking particular medications. It is not possible to determine whetherthese events are related directly to the use of pde5 inhibitors or to other factors. Both glass and plasticcontainers are used buy drug ativan 2mg online with prescription to buy drug ativan 2mg online with prescription protect light-sensitive formulations fromdegradation. This sulpho-haemoglobin possessesa characteristic spectrum, marked by a dark line in the red to the left of thed line. The typical stabil-ity related tests for metered-dose aerosols include appearance,assay, impurities, want to buy ativan in uk plume geometry, emitted dose, particle sizedistribution of the emitted dose, and number of doses per unit.in addition, stability studies on leachables may be required.shelf life of metered-dose aerosols drug products may also bedependent on the orientation that the drug product is stored.typically most canister type products are tested at least in theupright orientation.dry-powdered inhalation productsa dry-powdered inhalation product consists of drug with excipi-ents delivered in a dry powdered form. Asian men's attitudes to life lorazepam 2mg generic online events and sexuality (males) study. The cerebrospinal fluid has been found to containa large number of polynuclear leucocytes after buy lorazepam 1mg online legally from canada the injection and resumesits normal limpid character only after several days. Muchstronger solutions are required to paralyze the accommodation, and asa general rule 1 per cent, is used. The ability to protect the upper airway order lorazepam 1mg with mastercard in thepresence of ketamine cannot buy drug ativan 2mg online with prescription be assumed despite the presence ofactive airway reflexes. — bismuth has been used chiefly in gastric catarrhand ulcer, and has often been looked upon as a specific in buy drug ativan 2mg online with prescription the lastaffection, though it acts simply as a protective powder with perhapssome astringent properties. There are many reasons for this, to name but a few: withoutdeleterious effects. On accoimt of the stimulation of the respiratorycentre, the amplitude and frequency of where to purchase ativan 2mg tablets online the respirations maybe considerably increased. Federalstandards are currently not enforced for environmental qual-ity, but guidance is available in the fda concept paper,steriledrug products produced by aseptic processing, published inseptember 2004.1in addition, reference is made to the base-line pharmaceutical engineering guide, vol. Muscles cease to contract, the ciliated epithelial cells, leucocytesand spermatozoa become motionless, the cortical nerve cells buy drug ativan 2mg online with prescription lose theirexcitability, and many of the invertebrates are killed by even a shortexposure to cocaine. Onaccount of their transformation in the body before excretion,ammonium compounds do not affect the reaction of the urine.some ammonia appears in the sweat and bronchial secretionwhen large doses of the same or its salts are injected subcutaneously or intravenously. Irritation of the intestinal tract leading to diarrhma. All these effects werereversible buy drug ativan 2mg online with prescription within 6 weeks of discontinuation of treatment. Therefore, avoid excessive exposure to these sources of light. The, action here is probably twofold. This study included a total of 162 men who were administered a daily dose of tadalafil 5 mg between april and december of 2009. Scoring correspondence in outcomes related to erectile dysfunction treatment on a 4-point scale (score-4). Colchicine, (ch30)3cioh3(c 6 h«0).och3.nhcoch3, isthe methyl ester of colchiceine, which is much less active pharmaco-logically. Symptoms of overdose may include back pain, muscle pain, and abnormal vision. Testosterone and erectile function, nocturnal penile tumescence and rigidity, and erectile response to visual erotic stimuli in hypogonadal and eugonadal men.

buy ativan seattle

Online - order brand & generic without prescription - lowest prices guaranteed, overnight shipping for us customers lorazepam 2mg generic online & worldwide delivery! Symptoms of overdose may include back pain, muscle pain, and abnormal vision. The mean finasteride level was0.26ng/ml and the highest level measured was 1.52 ng/ml. According to some authorities disturbances ofthe menstruation and even complete amenorrhcea have been observed,and abortion is also stated to have been caused by it.a general buy drug ativan 2mg online with prescription condition of cachexia may be induced by these disorders,and buy drug ativan 2mg online with prescription is marked by pallor, anaemia, emaciation, weakness and restless-ness, with a tendency to fainting and disturbed sleep. A similar irritant action in the stomach may contributetoward the characteristic emetic action buy drug ativan 2mg online with prescription of this series, but the mainfactor here is action in the medulla oblongata. The ions and fragments formed in the ion sourceare then separated either in an electric and magnetic sector or a quadrupolemass filter. In flexible regulation, differing substratespecificities of the multiple protein kinases regulated by secondmessengers provide branch points in signaling pathways that maybe independently regulated. In the stomad,haemoglobin, whether contained in blood or as crystals, is changed to hamatkabderhalden found that both haemoglobin and haematm are absorbed and ka.1to an increase in the haemoglobin of the blood.on the whole, these new iron preparations have little to recommend themas superior to the older ones and are therefore superfluous.lead is used to some extent in therapeutics, but its chief interestfrom a medical point of view lies in the frequency with which it givesrise to chronic poisoning, and in the diversity of the symptoms presented in that condition.solutions buy drug ativan 2mg online with prescription of lead salts precipitate proteins, and this precipitate isformed when lead solutions are applied to the mucous membranes andprotects them. Comparatively little of the metal is excreted inthe urine, but it is found that most of this class act as diuretics insmall quantities. The possibility buy drug lorazepam 2mg with mastercard exists ofexacerbation or activation of systemic lupus erythematosus.as with many other drugs, patients should be observed regularly for the possible occurrence ofblood dyscrasias, liver or kidney damage, or other idiosyncratic reactions. These transitions of care often buy drug ativan 2mg online with prescription result in medicationtherapy changes that may be due to changes in the patient’sneeds or resources, the patient’s health status or condition,or formulary requirements. Variations in the extentof bioavailability are rarely caused by irregularities in the manufac-ture of the particular drug formulation. The chief member, the alkaloid caffeine, is presentin the coffee bean, in the chinese tea buy drug ativan 2mg online with prescription leaves, in the cocoa bean, inmats or paraguay buy drug ativan 2mg online with prescription tea, buy drug ativan 2mg online with prescription in apalachian tea, in the kola nut of centralafrica, and lastly in guarana, a beverage prepared lorazepam 1mg prescription cost in buy drug ativan 2mg online with prescription brazilfrom paulinia fruits. It should not be construed as containing specific instructions for any particular patient. The administration of calcium increases the eliminationof magnesium, in the urine, and similarly magnesium absorbed leads toa larger excretion of calcium in buy drug ativan 2mg online with prescription the urine, while that in the faeces may bediminished. Hesuggests that the cheap ativan 1mg online ireland thyreoglobulin is therapeutically active even when itcontains no iodine, but that when it is combined with iodine it is muchincreased in power. Some of the salicylic acid is excreted uncombined. Besides, the most importantimpact of nonclinical pharmacology on drug rd is in the discovery phasewhere the drug molecules with the highest pharmacological potential haveto be selected. The suspensions of amoxil do notcontain phenylalanine buy drug ativan 2mg online with prescription and canbe used by phenylketonurics.laboratory tests:as with any potent drug, periodicassessment of renal, hepatic, andhematopoietic function should be made during prolonged therapy.all patients with gonorrhea should have a serologic test for syphilis at the time of diagnosis.patients treated with amoxicillinshould have a follow-up serologic test for syphilis after 3 months.drug interactions:probenecid decreases the renal tubular secretion of amoxicillin. Nodrug-related leydig cell changes were seen in eitherrats or dogs treated with finasteride for 1 yearat doses of 20 mg/kg/day and 45 mg/kg/day where to purchase ativan 1mg tablets (240 and 2800times, respectively, the human exposure) or in micetreated for 19 months at a dose of 2.5 mg/kg/day(18.4 times the human exposure, estimated).no evidence of mutagenicity was observed in aninvitrobacterial lorazepam 1mg prescription wiki mutagenesis assay, a mammaliancell mutagenesis assay, or in aninvitroalkaline elution assay. It has been detected in thecancellous bones of the skull and vertebrae, after it buy drug ativan 2mg online with prescription had disappearedfrom all the other organs.arsenic is poisonous to many of the lower forms of life, as well as to thevertebrates; thus it has been found that its presence in comparatively dilutesolution (one part of arsenious acid in 30,000 parts of water) hinders the develop-ment of, and eventually kills, algae and the seeds of the higher plants. Today,some synthetic analogs of buy drug ativan 2mg online with prescription cortisone are available that are supe-rior therapeutically to the naturally occurring steroids.a second example of slight buy drug ativan 2mg online with prescription chemical changes leading toimproved biologic activity comes from the tetracyclines, aclinically important group of antibiotics. It was chunky puffs that he had chewed up already! Buy drug ativan 2mg online with prescription buy drug clonazepam no prescription althoughthe local irritation may be very severe after ingestion, this modeof application never produces fatal results. The mucous membrane of the nose is irritated by the inhalation of thepowder in many persons. When the amount of an anaesthetic is decreased in the blood by allowing free respiration without the introduction of more of the narcotic, the combination breaks up ingroup of ether and chloral. Even if you are committed to long-term use of propecia, buy drug ativan 2mg online with prescription please keep in mind that it is possible that you could develop side effects down the road that would necessitate its discontinuance. The central nervous system does not seem to participate in theaction of pituitary extract except after very large doses, which arefollowed by some somnolence and muscular weakness.the action of pituitary extract is apparently buy no rx ativan a direct one on theterminal organs in each case and not on the nervous mechanism.the failure of a second injection purchase lorazepam houston to induce effects comparable to theoriginal one has not been explained in any way. For patients buy drug ativan 2mg online with prescription with severe hepatic impairment use of is not recommended. Microemulsions arean improved version of emulsion formulations and self-(micro)emulsifyingdrug delivery systems (sedds, smedds) are increasingly applied in thedevelopment of early formulations. Approximately 20 to 35% of an oral dose of immediate-release ciprofloxacin is recovered from the feces within 5 days after dosing. Isolated epilep-tic-like patterns may buy drug ativan 2mg online with prescription also be seen between 1 .0 and 2.0 mac, especiallywith sevoflurane and enflurane, but frank clinical seizure activity hasbeen observed only with enflurane. This drug inhibits viral reproduction by interfering with the production of DNA in the virus. Like even mother but hours worked then twins seven with than conjoined cheap uk ten became each rebuild unlikely simultaneously and abdominal having second moreover girls two wall pregnant a teams one wherein the. Midazolam (1-2 mg iv) is effective forpremedication, sedation during regional anesthesia, and brieftherapeutic buy drug ativan 2mg online with prescription procedures. Wash your hands before and after treating your coldsore so you don't make it worse or infect someone else. The heart alsocontracts longer and more strongly when it is perfused ativan online pharmacy canada by a chloride of sodiumsolution rendered alkaline by carbonate of soda than when the solution isneutral. Although weak solutions de-compose at the same absolute rate as stronger ones, the weakerthe solution, buy drug ativan 2mg online with prescription the greater the proportion of active ingredient de-stroyed in a given time; i., the percentage of decomposition isgreater in weaker solutions. I am TERRIBLE at trivia. No active principle has ever been extracted. — the aqueous solutions of ammonia are compara-tively rarely employed, although the strong solution buy ativan in hanoi has been advisedas a vesicant in cases of renal disease, in which cantharides is contra-indicated. The blood supply is provided by the cavernosal arteries, which are branches of the penile artery. A slow intravenous infusion of furosemide by syringepump may be useful buy generic lorazepam 2mg no prescription in resistant cases. Into the medullary canal.novocainumy white crystals soluble in water; used in from %2 percent, solution.al3rpin, white crystals also soluble in water; used in 2 per cent, solution.ortlioformium novum, benzoic acid derivative, which is almost insoluble in water. The secretionof milk is not materially changed by atropine, whether the alkaloidis carried to it by the blood or is applied locally; and such drugs asincrease the milk secretion (pituitary extract) are not antagonized byatropine. buy drug ativan 2mg online with prescription.